Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Excellent
Based on 11 Reviews
9.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%**
Cholesterol
5 mg
2%
Total Omega 3 Polyunsaturates† providing: EPA (eicosapentaenoic acid) DHA (docosahexaenoic acid)
950 mg 504 mg378 mg
*** *** ***

Top Medical Research Studies

9
DHA reduces knee pain and swelling
We explored whether purified docosahexaenoic acid (DHA), an omega-3 fatty acid, can ease knee pain and swelling in a mouse model of arthritis. Mice with arthritis were treated with either oral or injected DHA, and we observed notable improvements in pain behavior and knee swelling.

This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
Read More
8
Omega-3 reduces knee pain effectively
We conducted a rigorous clinical trial to investigate how omega-3 fish oil affects knee pain in people aged 40 and older. In this double-blind study with four groups, we found that those taking an omega-3-based product, AvailOm, experienced a notable reduction in pain intensity compared to a placebo.

By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
Read More
8
Fish oil improves knee function
We explored the effects of omega-3 fish oil on knee osteoarthritis by evaluating 75 participants over 8 weeks. Divided into three groups, they took either 1,000 mg or 2,000 mg of fish oil each day.

Our findings showed that both dosages improved knee function and pain relief compared to a control group. However, the higher dose of 2,000 mg did not provide additional benefits over the 1,000 mg dose. Overall, participants reported high satisfaction with their results, and the treatment was deemed safe with minimal side effects.
Read More

Most Useful Reviews

10
Knee pain reduction
I ordered this for my parents, and now their knees have stopped hurting. This omega-3 is excellent; I highly recommend it to everyone.
Read More
10
Joint pain relief
Fantastic! I recommend it! This omega-3 is top-notch. After two months of taking 3 capsules daily, my mum's knee and shoulder joints no longer hurt.
Read More
9.5
Joint pain reduction
I order this for my mother regularly. The dosage is very good. Previously, she tried a smaller dosage from another brand but had nausea. This omega is different; after finishing a jar, the visual thickening in her finger joints decreased significantly, and new nails have grown straighter with nearly all pain gone.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
  • All Researches
9.5
Phytalgic promotes knee pain relief
We evaluated the effectiveness of Phytalgic, a supplement containing fish oil, on reducing knee pain in patients with osteoarthritis. In a randomized double-blind study of 81 participants, those taking Phytalgic reported lower usage of analgesics and NSAIDs compared to the placebo group.

Our findings showed significant reductions in pain, stiffness, and overall knee function, highlighting the potential benefit of Phytalgic in managing osteoarthritis symptoms. Overall, it seems that Phytalgic may offer an alternative relief option for those suffering from knee pain.
Read More
9
DHA reduces knee pain and swelling
We explored whether purified docosahexaenoic acid (DHA), an omega-3 fatty acid, can ease knee pain and swelling in a mouse model of arthritis. Mice with arthritis were treated with either oral or injected DHA, and we observed notable improvements in pain behavior and knee swelling.

This study highlights that DHA may reduce pain and inflammation in knee arthritis, suggesting it could be a helpful option for those suffering from rheumatoid arthritis. However, it’s essential to keep in mind that these results come from an animal model, and human studies are necessary.
Read More
8
Omega-3 reduces knee pain effectively
We conducted a rigorous clinical trial to investigate how omega-3 fish oil affects knee pain in people aged 40 and older. In this double-blind study with four groups, we found that those taking an omega-3-based product, AvailOm, experienced a notable reduction in pain intensity compared to a placebo.

By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
Read More
8
GLM protects against OA pain
We investigated how the green-lipped mussel (GLM) can help in managing knee pain caused by osteoarthritis (OA). In our study using a rat model, we induced OA and then administered GLM to see its effects on pain and cartilage health.

Results showed that GLM significantly improved pain levels while protecting against cartilage damage and inflammation. It also reduced markers associated with destructive processes in the joints.

This suggests that GLM could be a beneficial treatment option for those suffering from OA and associated knee pain.
Read More
This study focused on whether l-serine and EPA could help relieve chronic knee and low-back pain. We learned that 120 adults participated in a randomized, double-blind, placebo-controlled trial. They received either the active treatment or a placebo over an 8-week period.

After analyzing results, we found that l-serine and EPA significantly reduced pain scores. This suggests that these two substances may effectively alleviate discomfort for those suffering from persistent knee pain.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 11 Reviews
9.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Knee pain reduction
I ordered this for my parents, and now their knees have stopped hurting. This omega-3 is excellent; I highly recommend it to everyone.
Read More
10
Joint pain relief
Fantastic! I recommend it! This omega-3 is top-notch. After two months of taking 3 capsules daily, my mum's knee and shoulder joints no longer hurt.
Read More
9.5
Joint pain reduction
I order this for my mother regularly. The dosage is very good. Previously, she tried a smaller dosage from another brand but had nausea. This omega is different; after finishing a jar, the visual thickening in her finger joints decreased significantly, and new nails have grown straighter with nearly all pain gone.
Read More
9.5
Significant improvement
I took Omega with vitamin D3 as advised by my doctor. I felt noticeable improvement after 2 weeks—my knee pain has reduced significantly, and I've also started to lose weight pleasantly.
Read More
8.8
Improved knee health
I confirm my review with honesty. The large box contains 100 capsules, enough for 50 days. I've had a knock in my knees, but this has disappeared, and I've noticed better mood along with improvements to my skin, hair, and nails. The capsule smell is strong initially but fades after drinking water.
Read More

Frequently Asked Questions

Knee pain is a common condition that can result from various causes, including injuries, overuse, and underlying medical conditions such as arthritis. The knee joint is a complex structure composed of bones, ligaments, tendons, and cartilage, all of which work together to enable movement and support body weight. When any of these components are damaged or inflamed, it can lead to discomfort, stiffness, swelling, and reduced mobility in the affected area.

In many cases, knee pain can manifest as acute pain following an injury, such as a tear in a ligament or cartilage damage. Alternatively, it may develop gradually due to factors like repetitive strain, age-related degeneration, or conditions like osteoarthritis and rheumatoid arthritis. Treatment options vary widely and may include rest, physical therapy, medication, or, in severe cases, surgical interventions. If you're experiencing persistent knee pain, it's advisable to consult with a healthcare professional for an accurate diagnosis and tailored treatment plan.

Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.

Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.

Omega-3 fish oil has shown potential benefits for those experiencing knee pain, particularly when related to inflammatory conditions like arthritis. The omega-3 fatty acids, primarily EPA and DHA, possess anti-inflammatory properties that can help reduce joint inflammation and stiffness. Several studies suggest that supplementation with fish oil can lead to reductions in symptoms and improved joint function in individuals suffering from osteoarthritis or rheumatoid arthritis. However, the degree of effectiveness can vary among individuals, and additional factors such as the specific dosage and duration of use play a significant role in the outcomes.

It’s important to note that while fish oil may provide relief for some, it is not a cure-all solution. It’s always best to consult with a healthcare professional to discuss if omega-3 supplementation is appropriate for your specific condition, particularly if you’re currently taking other medications or have underlying health issues. Incorporating omega-3-rich foods, such as fatty fish, as well as maintaining an overall balanced diet and exercise routine, can further enhance joint health and may provide additional relief from knee pain.

Based on user reviews, the timeline to see results from this supplement for knee pain can vary. Some users report experiencing noticeable improvements within just two weeks of consistent use, as one individual mentioned a significant reduction in knee pain after that duration while taking Omega with vitamin D3, based on advice from their doctor (Read Review). Other users have indicated that it may take a longer period of about two months for substantial relief, as highlighted by a user whose mother saw her joint pain diminish after that timeframe with a daily dosage (Read Review).

Additionally, some individuals have reported improvements alongside other health benefits, such as better mood and skin quality, which can occur within a similar timeframe. For instance, one user noted that their knee issues disappeared and they experienced overall improvements in their health after using the product consistently (Read Review). Overall, while initial effects can be seen as soon as two weeks, more significant and lasting changes seem to occur after about two months of regular use.

The scientific research surrounding various supplements for knee pain offers promising insights. For instance, omega-3 fish oil has been shown to significantly reduce knee pain in adults over 40, highlighting a notable decrease in discomfort and improved quality of life among participants consuming AvailOm compared to a placebo [1]. Additionally, taking omega-3 fatty acids demonstrated pain relief in those with knee osteoarthritis [8]. Other studies have also indicated that omega-3 and EPA effectively alleviate chronic knee pain [5] and muscle soreness following exercise, suggesting a broader role for omega-3s in knee recovery [12].

In contrast, while krill oil provided some mild improvements in knee pain associated with osteoarthritis, its overall benefits were limited [2]. As for alternatives like the green-lipped mussel, research on animal models indicates potential benefits in managing knee pain and protecting against cartilage damage, but more human studies are needed for validation [3]. Overall, omega-3 fatty acids appear to have the strongest backing among supplements for knee pain management, making them a worthy consideration for those looking to mitigate joint discomfort.

Based on user reviews, many individuals have reported notable improvements in their symptoms when taking this omega-3 supplement. For instance, one user shared that after using the product, her parents' knee pain completely subsided, which led her to highly recommend it (Read Review). Another user noted that after two months of usage, both knee and shoulder joint pain in her mother disappeared (Read Review). Additionally, a user remarked that their knee pain significantly reduced within just two weeks, alongside enjoyable weight loss (Read Review).

Other transformations observed include decreased visual thickening in finger joints and improved nail growth with almost all pain alleviated (Read Review). Users have also noted improvements in mood and skin quality, showing a range of health benefits beyond joint relief (Read Review). While these testimonials portray a largely positive response to the supplement, it's essential to recognize that individual results can vary significantly based on personal health and lifestyle.

Users have reported positive experiences when combining this omega-3 supplement with other products for managing knee pain. Notably, one user mentioned that they took Omega with vitamin D3 as recommended by their doctor, leading to significant improvement in knee pain within just two weeks (Read Review). Additionally, several users highlighted that consistent use of this supplement not only alleviated their knee discomfort but also enhanced their overall joint health. For instance, one user noted that their mother no longer experienced pain in her knee and shoulder joints after two months of taking this omega-3 daily (Read Review).

Moreover, combining this supplement with other health routines appeared beneficial, as one user observed enhancements in mood and improvements in skin quality along with knee pain relief, showcasing a multi-faceted approach to health (Read Review). Overall, user testimonials suggest that supplementing with omega-3s, especially alongside vitamin D3 or as part of a broader regimen, can yield significant benefits for knee pain management.

When considering the optimal dose of Omega-3 fish oil for treating knee pain, the research indicates that dosages between 1,000 mg and 2,000 mg per day may be effective. A study with 75 participants showed improvements in knee function and pain relief when taking either of these doses over eight weeks. Interestingly, the 2,000 mg dosage did not yield significantly better outcomes compared to 1,000 mg, suggesting that higher doses might not be necessary for maximum benefits [8].

Moreover, another trial involving higher doses (4.5 g) of omega-3 showed some improvement in knee pain, but the response to a lower dose (0.45 g) was considered better, indicating that more isn't always better when it comes to fish oil [9]. Therefore, for those experiencing knee pain, a daily dosage of around 1,000 mg to 2,000 mg of Omega-3 fish oil is a well-supported guideline to potentially alleviate discomfort and improve function.

9.5
Significant improvement
I took Omega with vitamin D3 as advised by my doctor. I felt noticeable improvement after 2 weeks—my knee pain has reduced significantly, and I've also started to lose weight pleasantly.
10
Joint pain relief
Fantastic! I recommend it! This omega-3 is top-notch. After two months of taking 3 capsules daily, my mum's knee and shoulder joints no longer hurt.
8.8
Improved knee health
I confirm my review with honesty. The large box contains 100 capsules, enough for 50 days. I've had a knock in my knees, but this has disappeared, and I've noticed better mood along with improvements to my skin, hair, and nails. The capsule smell is strong initially but fades after drinking water.
10
Knee pain reduction
I ordered this for my parents, and now their knees have stopped hurting. This omega-3 is excellent; I highly recommend it to everyone.
9.5
Joint pain reduction
I order this for my mother regularly. The dosage is very good. Previously, she tried a smaller dosage from another brand but had nausea. This omega is different; after finishing a jar, the visual thickening in her finger joints decreased significantly, and new nails have grown straighter with nearly all pain gone.
8
Omega-3 reduces knee pain effectively
We conducted a rigorous clinical trial to investigate how omega-3 fish oil affects knee pain in people aged 40 and older. In this double-blind study with four groups, we found that those taking an omega-3-based product, AvailOm, experienced a notable reduction in pain intensity compared to a placebo.

By week eight, participants reported less discomfort and improved quality of life. Additionally, the intake of AvailOm led to better muscle strength and sleep quality, making it a promising option for alleviating persistent knee pain. Overall, omega-3 fish oil shows effective benefits for older adults struggling with knee pain.
8
Fish oil improves knee function
We explored the effects of omega-3 fish oil on knee osteoarthritis by evaluating 75 participants over 8 weeks. Divided into three groups, they took either 1,000 mg or 2,000 mg of fish oil each day.

Our findings showed that both dosages improved knee function and pain relief compared to a control group. However, the higher dose of 2,000 mg did not provide additional benefits over the 1,000 mg dose. Overall, participants reported high satisfaction with their results, and the treatment was deemed safe with minimal side effects.
This study focused on whether l-serine and EPA could help relieve chronic knee and low-back pain. We learned that 120 adults participated in a randomized, double-blind, placebo-controlled trial. They received either the active treatment or a placebo over an 8-week period.

After analyzing results, we found that l-serine and EPA significantly reduced pain scores. This suggests that these two substances may effectively alleviate discomfort for those suffering from persistent knee pain.
7
Omega-3 alleviates muscle soreness
We investigated how omega-3 fatty acids could affect knee pain related to delayed onset muscle soreness after eccentric exercises. Using a randomized and double-blinded study design, we observed 27 untrained men before and after they engaged in specific exercises.

Although participants reported their pain levels alongside measurements of knee range of motion and thigh circumference, we found that omega-3 supplementation showed promise in alleviating muscle soreness. Overall, the findings suggest that omega-3 may be helpful for enhancing recovery after such exercise.
7
Modest benefits of krill oil
We investigated whether krill oil could help reduce knee pain in adults experiencing mild to moderate osteoarthritis. Over six months, participants took either krill oil or a placebo in a well-structured double-blind trial.

While the results showed that krill oil was safe and led to some modest improvements in knee pain, stiffness, and physical function, the overall benefits were limited.

Thus, while krill oil may serve as a mild alternative for osteoarthritis pain relief, it’s essential to manage expectations regarding its effectiveness.
8
GLM protects against OA pain
We investigated how the green-lipped mussel (GLM) can help in managing knee pain caused by osteoarthritis (OA). In our study using a rat model, we induced OA and then administered GLM to see its effects on pain and cartilage health.

Results showed that GLM significantly improved pain levels while protecting against cartilage damage and inflammation. It also reduced markers associated with destructive processes in the joints.

This suggests that GLM could be a beneficial treatment option for those suffering from OA and associated knee pain.
We examined whether high-dose fish oil could better relieve knee osteoarthritis symptoms than a low dose. In a thorough trial involving 202 participants, they were divided into groups receiving either high-dose (4.5 g omega-3) or low-dose fish oil (0.45 g omega-3) for up to two years.

While both groups experienced some improvement in knee pain and function, the low-dose group responded better overall. There was no significant difference in cartilage loss or other health outcomes, leading us to conclude that higher doses may not be more effective and warrant further research into alternative oil blends.

References

  1. Pérez-Piñero S, Muñoz-Carrillo JC, Victoria-Montesinos D, García-Muñoz AM, Andreu-Caravaca L, et al. Efficacy of Extract and/or an Omega-3-Based Product for Improving Pain and Function in People Older Than 40 Years with Persistent Knee Pain: A Randomized Double-Blind Controlled Clinical Trial. Nutrients. 2023;15. doi:10.3390/nu15173848
  2. Stonehouse W, Benassi-Evans B, Bednarz J, Vincent AD, Hall S, et al. Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2022;116:672. doi:10.1093/ajcn/nqac125
  3. Jhun J, Na HS, Cho KH, Kim J, Moon YM, et al. A green-lipped mussel reduces pain behavior and chondrocyte inflammation and attenuated experimental osteoarthritis progression. PLoS One. 2021;16:e0259130. doi:10.1371/journal.pone.0259130
  4. VanDusseldorp TA, Escobar KA, Johnson KE, Stratton MT, Moriarty T, et al. Impact of Varying Dosages of Fish Oil on Recovery and Soreness Following Eccentric Exercise. Nutrients. 2020;12. doi:10.3390/nu12082246
  5. Sasahara I, Yamamoto A, Takeshita M, Suga Y, Suzuki K, et al. l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J Nutr. 2020;150:2278. doi:10.1093/jn/nxaa156
  6. Valdes AM, Ravipati S, Menni C, Abhishek A, Metrustry S, et al. Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans. Sci Rep. 2017;7:10748. doi:10.1038/s41598-017-09516-3
  7. Sibille KT, King C, Garrett TJ, Glover TL, Zhang H, et al. Omega-6: Omega-3 PUFA Ratio, Pain, Functioning, and Distress in Adults With Knee Pain. Clin J Pain. 2018;34:182. doi:10.1097/AJP.0000000000000517
  8. Peanpadungrat P. Efficacy and Safety of Fish Oil in Treatment of Knee Osteoarthritis. J Med Assoc Thai. 2015;98 Suppl 3:S110.
  9. Hill CL, March LM, Aitken D, Lester SE, Battersby R, et al. Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose. Ann Rheum Dis. 2016;75:23. doi:10.1136/annrheumdis-2014-207169
  10. Torres-Guzman AM, Morado-Urbina CE, Alvarado-Vazquez PA, Acosta-Gonzalez RI, Chávez-Piña AE, et al. Chronic oral or intraarticular administration of docosahexaenoic acid reduces nociception and knee edema and improves functional outcomes in a mouse model of Complete Freund's Adjuvant-induced knee arthritis. Arthritis Res Ther. 2014;16:R64. doi:10.1186/ar4502
  11. Jacquet A, Girodet PO, Pariente A, Forest K, Mallet L, et al. Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. Arthritis Res Ther. 2009;11:R192. doi:10.1186/ar2891
  12. Tartibian B, Maleki BH, Abbasi A. The effects of ingestion of omega-3 fatty acids on perceived pain and external symptoms of delayed onset muscle soreness in untrained men. Clin J Sport Med. 2009;19:115. doi:10.1097/JSM.0b013e31819b51b3
image